San Francisco, California

The 20 Best Botox Providers in San Francisco, CA

From Hayes Valley and Nob Hill to the Marina, Union Square and Presidio Heights, San Francisco is dense with injectors — this list narrows it to the twenty clinics with the strongest verified track records. Every provider below was ranked using publicly available Google review data: star rating weighted by review volume, so a 5.0 from 12 people doesn't outrank a 4.9 from hundreds.

20Top providers
3,382Reviews analyzed
Aug 2026Last updated
The ranking

San Francisco's top-rated Botox clinics

Filter by clinic name, neighborhood or ZIP code to narrow the list.

1

Nob Hill Aesthetics | Medical Spa

★★★★★4.9923 Google reviews

909 Hyde St Unit 415, San Francisco, CA 94109 · Lower Nob Hill

Nob Hill Aesthetics is the epitome of luxury in San Francisco's Nob Hill district, offering state-of-the-art laser skin care and body contouring services. Our holistic approach focuses on enhancing natural beauty through non-surgical, non-invasive procedures, expertly tailored to slow down the aging process. From Botox and Juvederm…

I’ve been receiving Botox treatments here for about 2 1/2 years and have only good things to say. The team here is incredible. The membership plan allows for flexible payment options and reduced price per unit of Botox, which is super convenient. Everyone who asks me about my Botox I say “Go to Nob Hill Aesthetics!!”

★★★★★ · May 2026
Medical spaSkin care clinicWeight loss service
2

Mabrie Facial Institute

★★★★★4.9472 Google reviews

166 Geary St Fl 1300, San Francisco, CA 94108 · Union Square

Mabrie Facial Institute, led by facial plastic surgeon Dr. David C. Mabrie, serves San Francisco and the Bay Area with non-surgical facial rejuvenation using injectables exclusively. Voted Best BOTOX and Best Medical Spa in the Bay Area by SFGate, the practice takes a structure-first approach to full-face balance, including the i360 Full…

I cannot say enough good things about Dr. Mabrie and the MFI team! I went in for filler and Botox and Dr Mabrie has completely restored my under eyes. I feel like myself again! Huge confidence boost, and recommend him to anyone who is on the fence!

★★★★★ · July 2026
Medical spaCosmetic surgeon
3

Hayes Valley Medical Esthetics – Hayes Valley

★★★★★4.9279 Google reviews

182 Gough St, San Francisco, CA 94102 · Civic Center

Voted Best Med Spa by SF Magazine, Hayes Valley Medical Esthetics (HVME) was founded in 2014 by Linda Behla, RN, and Board-Certified Plastic Surgeon Yngvar A. Hvistendahl, MD. We offer boutique medical clinics in Downtown Larkspur, Marin, and San Francisco’s Cow Hollow and Hayes Valley neighborhoods. Expect safe, personalized, and…

I had had my lips enhanced along with Botox injections and I’m very happy with the results of my lips (Botox it’s too soon to tell). They look natural anti the fullness that I desired . I saw Melanie who is the upmost professional and quite personable. Everyone from the front desk are also quite personable. This is my third visit to this medispa and I have been very pleased with my results every time . I highly…

★★★★★ · April 2026
Medical spaSkin care clinic
4

Serenity Wellness Spa

★★★★★4.9229 Google reviews

2087 Union St #2, San Francisco, CA 94123 · Union Street

Serenity Wellness Spa partners with talented, giving practitioners, to create a spa experience that improves people’s well being. We offer Massage, Facials, Body Wraps, Wood Therapy and Cryoskin Slimming and Toning treatments. We want everyone to feel and look their best at any age.

SpaDay spaFacial spa
5

Serenity Aesthetics & Wellness

★★★★☆4.5316 Google reviews

126 Post St 2nd floor, San Francisco, CA 94108 · Union Square

Serenity Aesthetics & Wellness, located in San Francisco and Burlingame, offers advanced aesthetics and functional health treatments. The spa provides a range of treatments, including Botox, fillers, laser skin resurfacing, and body contouring. Our Functional Health program offers weight loss injections, hormone replacement therapy,…

I had the pleasure of working with Nurse Nia. I rarely write reviews, but I am so INCREDIBLY HAPPY and moved by my results with Nurse Nia, that I must pay a good thing forward. Nurse Nia designed a treatment plan for me that has completely revitalized my appearance and restored a bit of confidence that I felt I had lost. I turned 40 this year, and for the past couple years l've noticed I always look tired. My skin…

★★★★★ · April 2025
Medical spaHealth consultantSkin care clinic
6

Hayes Valley Medical Esthetics - Cow Hollow/Marina

★★★★★4.9176 Google reviews

3214 Fillmore St, San Francisco, CA 94123 · Union Street

Founded in 2014 by Linda Behla, RN, and medically supervised by Yngvar A. Hvistendahl, MD, Hayes Valley Medical Esthetics offers boutique medical clinics in Downtown Larkspur, Marin and San Francisco’s Cow Hollow and Hayes Valley neighborhoods. Expect safe, personalized, and effective treatments utilizing tested technologies, combination…

Team is high class and always makes this a lovely experience for me! They clean the area well and seriously don’t even feel when they inject. This is such a change from my last Botox spot and truly worth the price!

★★★★★ · July 2026
Medical spaFacial spaSkin care clinic
7

SkinSpirit Presidio Heights

★★★★★4.8172 Google reviews

3325 Sacramento St, San Francisco, CA 94118 · Presidio Heights

SkinSpirit Presidio Heights is one of San Francisco’s premier medical spas, serving the Marina and Cow Hollow neighborhoods. Located near Presidio Park, our clinic is where you'll find the city’s top aestheticians and medical providers, who are committed to improving the overall health of your skin and delivering natural-looking results.…

I cannot recommend Maria enough. She is incredibly talented, thoughtful, and truly has an amazing eye for facial aesthetics. I recently had full facial balancing with filler, including my jawline and chin, and I honestly could not be happier with the results. Everything looks so natural, beautifully balanced, and still completely like me—just more refreshed, defined, and confident. Over our sessions, she’s done…

★★★★★ · May 2026
Medical spaSkin care clinic
8

ParlourRx

★★★★★5127 Google reviews

2030 Union St Suite 300C, San Francisco, CA 94123 · Union Street

Located in the heart of San Francisco's Marina District, ParlourRx is a boutique medical spa dedicated to delivering refined and natural-looking aesthetic results. Opened in 2022, the practice combines the expertise of a seasoned team with a personalized approach to beauty. Specializing in injectable and advanced skin treatments,…

Juli is amazing and I absolutely recommend her!! I went to her for my first time getting Botox so I had no idea what I needed or what to expect. I had a virtual consultation with her where she explained the process and gave me a rundown of what she would recommend. Then on the day of my appointment we had another, very detailed consultation on why she suggested each area she was going to treat. The process of…

★★★★★ · February 2025
Medical spaMedical office
9

REJUV Medical

★★★★★4.998 Google reviews

255 King St # A, San Francisco, CA 94107 · Mission Bay

REJUV Medical, nestled in the heart of San Francisco, offers a comprehensive range of medical aesthetics, concierge medical services, and holistic treatments since its inception in August 2022. Our highly experienced providers are dedicated to enhancing your natural beauty and promoting overall wellness. From medical-grade skincare and…

So glad I found Renew! You always take a chance when picking a random place off the internet, but the great reviews made me hopeful—and they were right. I received my first-ever treatment of Daxxify and I am thrilled. After years of Botox, I can’t believe how this worked practically instantly! The price was so reasonable that when I told a friend, they were shocked at what a great deal I got. ​Christina is truly a…

★★★★★ · March 2026
Medical spaAlternative medicine practitionerHolistic medicine practitioner
10

Urban Allure Medical Spa

★★★★★588 Google reviews

660 Market St #225, San Francisco, CA 94104 · Union Square

Discover the epitome of skincare excellence at Urban Allure Medical Spa, located at 230 California Street Suite 603, San Francisco. As a premier medical spa, we specialize in personalized aesthetic treatments with services including Botox, Coolsculpting, Laser Hair Removal, Dermal Fillers, Chemical Peels, and Microneedling. Our expert…

I’ve been going to Urban Allure for over a year, for Botox and monthly facials. I was previously going to a chain provider, but price gouging and “mean girl” energy made me look for someplace new. As soon as I met Erin and Emily, I knew that I would never go anywhere else! They are both incredibly kind, knowledgeable, and treat every session with care. My skin feels and looks so much better since starting at Urban…

★★★★★ · May 2026
Medical spaBeauty product supplierFacial spa
11

The G Spa San Francisco

★★★★★4.893 Google reviews

460 Post St, San Francisco, CA 94102 · Union Square

The G Spa San Francisco, a premiere medspa, is brought to you by Dr. Grenier and the physicians of Downtown Medical Group. Our mission at The G Spa is to help and motivate our clients to live healthier. Our services are carefully procured to meet our physicians goals to enrich and let our clients age gracefully over time.

Danielle is amazing! She has the best hands for Botox and always delivers beautiful, natural results. I've followed her for a few years because she's truly excellent. Highly recommend!

★★★★★ · June 2026
Medical spaAlternative medicine practitionerFacial spa
12

Aura Skin Spa

★★★★★4.784 Google reviews

118 Columbus Ave, San Francisco, CA 94133 · Jackson Square

Aura Skin Spa is a medical day spa in San Francisco that has been in business for 17 years and is dedicated to providing results oriented skin care treatments that will restore and maintain the health and beauty of your skin. By combining a balance of FDA-approved treatments and select aesthetic procedures, such as Botox, dermal fillers,…

I had such a wonderful experience! Satira and Justin at the front desk were incredibly sweet and welcoming from the moment I walked in, they made the whole visit feel comfortable and easy. And Claire did an amazing job with my Botox professional, attentive, and really took the time to make sure I felt confident about everything. I Highly recommend this team to anyone looking for great service and genuine care!

★★★★★ · July 2026
Medical spaDay spaDermatologist
13

Evergreen Aesthetics

★★★★★4.963 Google reviews

364 Hayes St Second Floor, San Francisco, CA 94102 · Civic Center

Simple, effective, medical-grade skincare and aesthetic treatments that are customized for each patient. Evergreen Aesthetics is led by a Aesthetic Nurse Practitioner with over 10 years experience in the field who specializes in minimal-downtime rejuvenation, including injectables, lasers, body contouring, and esthetician services. Our…

I had such an amazing experience here! Taryn is incredibly professional, kind, and knowledgeable — she took the time to explain every step of the process, which made me feel super comfortable and well taken care of. I got Botox and was honestly shocked by how painless it was — I barely felt a thing, and the results are so natural and smooth. I also tried the laser hair removal, and they use the latest machine,…

★★★★★ · April 2025
Medical spa
14

SKIN Medical Spa

★★★★★4.861 Google reviews

1825 Union St, San Francisco, CA 94123 · Union Street

SKIN Medical Spa is the most established and trusted provider of non-invasive, medical aesthetic procedures in the city. Founded in 2005 by Dr. Robert Colvin and conveniently located in the heart of the trendy Cow Hollow neighborhood of San Francisco, we specialize in injectables, laser treatments, medical facials, body contouring, and…

So I had Botox here. They are very polite professional, but I was not happy with the results. I got 30 shot of the Botox and I could still frown easily. Even after the two weeks. To be fair they told me to go back if I feel it wasn’t enough but I was traveling and i never had this experience that I need to go back

★★☆☆☆ · July 2026
Medical spaSkin care clinic
15

Eternia Medspa

★★★★★546 Google reviews

170 Grant Ave 4th Floor, San Francisco, CA 94108 · Union Square

Eternia Medspa is a luxury aesthetic destination in the Bay Area dedicated to timeless beauty and natural results. Led by top 100 injector and national trainer Nurse Nia, our treatments blend artistry and advanced science to rejuvenate, sculpt, and refine. We specialize in Botox, dermal fillers, PRF, PDO threads, skin tightening, and…

I have been seeing Nia for over seven years and have followed her through multiple practices because she is simply the best at what she does. Her expertise, consistency, and attention to detail give me complete confidence, which matters a lot when it comes to aesthetic treatments. She recently opened her own spa, and it reflects everything that makes her exceptional. The space is professional and welcoming, and she…

★★★★★ · February 2026
Medical spaHealth spaPlastic surgery clinic
16

MedEstheticsRX

★★★★★531 Google reviews

2300 Sutter St Ste 303, San Francisco, CA 94115 · Lower Pacific Heights

MedEstheticsRX in San Francisco, CA offers advanced skincare treatments designed to target a wide range of skin concerns using proven techniques & premium skincare beauty products. Our skincare treatment services include dermaplaning, chemical peels, microdermabrasion, and micro needling, all tailored to improve skin texture and tone. We…

Skin care clinicDermatologist
17

Laser Clear Skin MedSpa

★★★★★530 Google reviews

414 Francisco St, San Francisco, CA 94133 · North Beach

At Laser Clear Skin MedSpa, we combine advanced aesthetics with medical expertise to help you look and feel your best. Our RN-led team specializes in laser skin rejuvenation, acne and pigmentation treatments, PRP hair restoration, microneedling, and GLP-1 weight loss programs. Located in San Francisco, we deliver safe, results-driven…

Medical spaWeight loss service
18

Dr. Sheena Kong Med Spa

★★★★☆4.543 Google reviews

490 Post St Ste 1150, San Francisco, CA 94102 · Union Square

Dr. Sheena Kong Medical Spa offers a luxurious haven where beauty meets advanced medical expertise. Nestled in the heart of San Francisco, our spa specializes in a blend of innovative aesthetic treatments and timeless skincare solutions. Dr. Kong, a renowned board-certified physician, leads our team of professionals in providing…

I have trusted Dr Kong for several years with my medical aesthetics. She is an expert in keeping me looking both young and healthy. What I like most is her ability to make all the work look natural. I have done many different treatments (Bellafil, Xeomin, Botox, Ultherapy, Coolsculpting) with her and all have been done with kindness respect and the utmost care. This year, we did a series trifecta of treatments-…

★★★★★ · June 2024
Medical spaDoctor
19

NursUrSkin

★★★★★527 Google reviews

2500 Clay St, San Francisco, CA 94115 · Pacific Heights

Nueromodulators Botox Juvaderm Sculptra Radiesse Skinvive Dermal Fillers Biostimulatory Fillers Skin Care Consultations Microneedle Ariessence Skin Botox PRP/PRF UnderEye Fillers Lip Fillers Cheek Fillers Facial Rejuvination Facial Balancing VI Chemical Peels Skin Tag Removal Jessner

Stephani is not only amazing at what she does, she’s also sweet, professional, fun to talk to, and knowledgeable. I get Botox from her about every 3 months. I could not be happier with my natural, yet perfect results! Since seeing her I feel more confident, my makeup stays on better and my skin looks AMAZING. Stephani is your go to for all things skin.. you won’t be disappointed!

★★★★★ · March 2023
Medical spaBeauty salonFacial spa
20

Premier Wellness & Aesthetics Center

★★★★★524 Google reviews

490 Post St Ste 913, San Francisco, CA 94102 · Union Square

Premier Wellness & Aesthetics Center is a physician-led medical spa in San Francisco offering medically guided hormone therapy, testosterone replacement therapy (TRT), hormone replacement therapy (HRT), longevity planning, stem cell-focused regenerative wellness consultations, Botox, fillers, and skin-focused aesthetic care. Dr. Harlan…

Medical spaFacial spaHealth spa

How we ranked them

  • Verified review data. We pulled current Google Business Profile data for med spas and aesthetic clinics across the San Francisco metro.
  • Weighted scoring. Each clinic's average star rating is multiplied by a logarithmic factor of its review count, so consistency at volume beats a handful of perfect scores.
  • Active locations only. Permanently and temporarily closed listings were removed, and duplicate locations of the same brand were consolidated.
  • No paid placement. Nobody paid to appear here, and no clinic can buy a higher spot.

Ratings change constantly — always confirm credentials, licensing and pricing directly with the clinic before booking. Read our guide on how to choose a qualified injector first.